Mixing Cyclobenzaprine and Alcohol Interactions and Dangers

Is Cyclobenzaprine addictive? Despite its ease of access, Flexeril can lead to abuse, tolerance, physical dependence, and addiction, especially when combined with alcohol or opioids.


Flexeril (cyclobenzaprine) is a muscle relaxant that intercepts pain signals to the brain. Typically, musculoskeletal problems like pain, injury, or spasms are addressed with its prescription. Alcohol and muscle relaxants, like Flexeril, can have serious side effects that include increased drowsiness, impaired motor and cognitive function, chemical dependence, and even accidental death.

Moreover, using these drugs at the same time raises the risk of several side effects, such as respiratory depression, overdose, increased vulnerability to injuries and falls, car crashes, seizures, and more. The central nervous system (CNS) is depressed by both alcohol and muscle relaxants. This combined effect significantly increases the likelihood of multiple risks, underscoring the significance of never combining these substances.

If you or someone you know is suffering from Cyclobenzaprine and alcohol addiction, We Level Up Treatment Centers can help. Speak with our hotline specialists and discover the support and professional-accredited addiction treatment programs we offer.


What Is Cyclobenzaprine?

Cyclobenzaprine is a muscle relaxant medication commonly used to treat muscle spasms and discomfort associated with acute musculoskeletal conditions. It is often prescribed for muscle strains, sprains, and injuries. Cyclobenzaprine is believed to work by affecting the signals between the nerves and the muscles, helping to reduce muscle spasms.

Cyclobenzaprine is typically used as a short-term treatment, usually for a few weeks, to provide relief during the acute phase of muscle-related injuries. It is not recommended for long-term use, as its effectiveness may decrease, and there are potential side effects.

Cyclobenzaprine is the generic name for the medication, but it is also sold under various brand names. Some of the common brand names for cyclobenzaprine include:

  1. Flexeril: One of the most widely known brand names for cyclobenzaprine.
  2. Amrix: Amrix is an extended-release formulation of cyclobenzaprine.
  3. Fexmid: Fexmid is another brand name for the immediate-release form of cyclobenzaprine.

These brand names may be used interchangeably with the generic name, and the choice of which version to prescribe can depend on factors such as the specific needs of the patient and the healthcare provider’s preference.

Can You Drink Alcohol With Cyclobenzaprine?

It is generally advised to avoid drinking alcohol while taking cyclobenzaprine. Combining the two can increase the risk of central nervous system depression, leading to heightened drowsiness, dizziness, and impaired coordination. Alcohol may intensify the side effects of cyclobenzaprine, making it unsafe to operate machinery or engage in activities requiring mental alertness. Always consult a healthcare professional for personalized advice based on your health condition and medications.

Misuse Of Cyclobenzaprine With Alcohol

Misusing cyclobenzaprine with alcohol is not uncommon, although it is not typically sought after for recreational purposes. Cyclobenzaprine is a muscle relaxant prescribed to alleviate muscle spasms and discomfort due to musculoskeletal conditions. However, some individuals may misuse or abuse it, often in combination with alcohol, to enhance its soothing effects or for recreational purposes.

Combining cyclobenzaprine with alcohol can amplify the depressant effects on the central nervous system. This can result in heightened drowsiness, dizziness, impaired coordination, and an increased risk of accidents or injuries. Moreover, the combination of cyclobenzaprine and alcohol can lead to severe respiratory depression, a potentially life-threatening condition where breathing becomes slow and shallow.

How Long After Taking Cyclobenzaprine Can I Drink Alcohol?

The specific timeline for when it is safe to drink alcohol after taking cyclobenzaprine can vary based on individual factors such as metabolism, overall health, and the particular dosage of the medication. However, as a general guideline, it is advisable to wait at least several hours after taking cyclobenzaprine before consuming alcohol.

Cyclobenzaprine has a relatively long half-life, meaning it stays in the system for a significant time. The medication’s effects can last for several hours, and combining it with alcohol during this period can lead to enhanced central nervous system depression.

To ensure safety and minimize potential risks, it’s recommended to consult with your healthcare provider for personalized advice regarding the specific timing and interaction between cyclobenzaprine and alcohol based on your circumstances. Always follow your healthcare provider’s instructions and avoid self-adjusting medication or alcohol intake without their guidance.

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Cyclobenzaprine is a muscle relaxant that works by affecting the communication between nerves in the central nervous system and the muscles
Cyclobenzaprine is a muscle relaxant that works by affecting the communication between nerves in the central nervous system and the muscles.

Cyclobenzaprine Side Effects With Alcohol

Combining cyclobenzaprine with alcohol can lead to an increased risk of side effects, as both substances can depress the central nervous system. Here are some potential side effects that may be exacerbated when cyclobenzaprine is taken with alcohol:

  1. Drowsiness and Sedation: Both cyclobenzaprine and alcohol can cause drowsiness. This effect is likely more pronounced when taken together, leading to excessive sleepiness or sedation.
  2. Dizziness and Impaired Coordination: Both substances can cause dizziness and impaired coordination. Combining them may intensify these effects, increasing the risk of falls or accidents.
  3. Cognitive Impairment: Alcohol and cyclobenzaprine can impair cognitive function. When used together, this may result in difficulty concentrating and decreased mental alertness.
  4. Risk of Overdose: Both alcohol and cyclobenzaprine can depress the central nervous system. Combining them increases the risk of overdose, which can be characterized by severe respiratory depression, unconsciousness, and, in extreme cases, can be life-threatening.

Individual responses to medications and alcohol can vary, and the severity of these effects may depend on factors such as the dosage of cyclobenzaprine, personal tolerance, and overall health. It is strongly recommended to consult with a healthcare professional before combining cyclobenzaprine with alcohol. See medical attention immediately if you experience any unusual or severe side effects.

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Even if you have failed previously and relapsed, or are in the middle of a difficult crisis, we stand ready to support you. Our trusted behavioral health specialists will not give up on you. When you feel ready or just want someone to speak to about therapy alternatives to change your life call us. Even if we cannot assist you, we will lead you to wherever you can get support. There is no obligation. Call our network hotline today.

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Cyclobenzaprine Food And Drug Interactions

Cyclobenzaprine can interact with certain foods and drugs, potentially affecting its efficacy or leading to an increased risk of side effects. It’s important to discuss all medications, including over-the-counter medicines and dietary supplements, with your healthcare provider. Here are some interactions to be aware of:

  1. Monoamine Oxidase Inhibitors (MAOIs): Concurrent use of cyclobenzaprine with MAOIs, a class of antidepressants, can lead to serious side effects, including hypertensive crisis. Allow a sufficient time gap between discontinuing MAOIs and starting cyclobenzaprine.
  2. Sedative Medications: Combining cyclobenzaprine with other sedatives, such as benzodiazepines or certain antihistamines, can increase central nervous system depression, leading to heightened drowsiness and impaired coordination.
  3. Alcohol: As previously mentioned, alcohol can intensify the sedative effects of cyclobenzaprine, leading to increased drowsiness and impaired cognitive and motor functions.
  4. Grapefruit Juice: Grapefruit juice may inhibit the metabolism of cyclobenzaprine, potentially leading to increased blood levels of the medication. This interaction could amplify side effects and should be discussed with a healthcare provider.
  5. Urinary Acidifying Agents: Drugs or substances that acidify urine may decrease the elimination of cyclobenzaprine from the body. This interaction could lead to increased levels of the drug and an extended duration of its effects.

Interactions of Cyclobenzaprine with Other Medications

Cyclobenzaprine oral tablet has the potential to interact with various medications, vitamins, or herbs a person might be using concurrently. An interaction occurs when a substance alters the way a drug functions, which can be detrimental or impede the effectiveness of the drug.

To minimize the risk of interactions, your doctor must closely monitor all medications you take. Make sure to inform your doctor about all medications, including vitamins or herbs, that you are using. For specific information on how this drug might interact with other substances you’re consuming, consult your doctor or pharmacist.

Medications to Avoid with Cyclobenzaprine

Avoid taking monoamine oxidase inhibitors (MAOIs) with Cyclobenzaprine, as it can lead to severe effects on the body. Examples of these drugs include selegiline, rasagiline, and tranylcypromine. Combining this drug with an MAOI or doing so within 14 days of discontinuing an MAOI could heighten the risk of severe side effects, such as seizures.

Interactions Escalating the Risk of Side Effects

Certain medications, when taken with Cyclobenzaprine, can increase the likelihood of side effects due to elevated levels of Cyclobenzaprine in the body. These include:

  • Benzodiazepines like triazolam, alprazolam, and midazolam can intensify sedation and drowsiness.
  • Barbiturates such as phenobarbital can lead to heightened sedation and drowsiness.
  • Drugs used for treating depression, including fluoxetine, venlafaxine, amitriptyline, or bupropion, might elevate the risk of serotonin syndrome.
  • Anticholinergic medications like tolterodine or oxybutynin may increase the likelihood of specific side effects like dry mouth or urinary retention.

Interactions Intensifying the Effect of Cyclobenzaprine

Some medications, when combined with Cyclobenzaprine, may result in more pronounced side effects such as increased drowsiness or sedation. It is crucial to consult a doctor about the safety of using another medication along with Cyclobenzaprine and to avoid operating machinery while taking it.

The Dangers of Misusing Cyclobenzaprine

Misuse of Flexeril can potentially lead to overdose, particularly when combined with substances like alcohol. Overdosing on Flexeril might result in severe complications such as cardiac arrest, dangerously low blood pressure, central nervous system depression, or seizures. In case of suspicion that someone has ingested a large quantity of the drug, immediate support should be sought without delay.

Data spanning back to the early 2000s highlights an escalating trend of emergency department visits associated with cyclobenzaprine misuse. In 2010, around 12,411 emergency room visits were estimated to be linked to cyclobenzaprine, marking a notable increase of approximately 101% from 6,183 visits in 2004.

Vulnerability Factors for Cyclobenzaprine Abuse

While anyone can develop a Flexeril addiction, certain factors heighten the susceptibility of specific individuals to developing a problem:

  • Personal history of substance or alcohol abuse.
  • Family history of substance or alcohol abuse.
  • Frequent exposure to drug-oriented environments.
  • History of mental health conditions.
  • Lack of awareness about the addictive nature of prescription drugs.
Cyclobenzaprine is typically used as a short-term treatment for muscle spasms and associated pain. It is often prescribed with rest and physical therapy to help relieve discomfort caused by muscle strains and sprains.
Cyclobenzaprine is typically used as a short-term treatment for muscle spasms and associated pain. It is often prescribed with rest and physical therapy to help relieve discomfort caused by muscle strains and sprains.

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Cyclobenzaprine Addiction Statistics

Understanding the scope and impact of Flexeril (cyclobenzaprine) addiction is essential for addressing this issue. By examining Flexeril addiction statistics, we can gain insights into the prevalence, trends, and consequences associated with the misuse and abuse of this medication. These statistics shed light on the challenges faced by individuals and communities affected by Flexeril addiction, highlighting the need for awareness, prevention, and effective treatment strategies.


0.2%

Roughly 0.2% of individuals aged 12 and older in the US reported misusing cyclobenzaprine (the generic name for Flexeril) in 2018.

Source: SAMHSA

2003 to 2015

JAMA Network Open found that the misuse of muscle relaxants, including cyclobenzaprine, increased significantly during this period.

Source: JAMA Network Open

79.1%

From 2004 to 2015, cyclobenzaprine-related emergency department visits increased by 79.1%.

Source: Journal of Addiction Medicine


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Treatment for Addiction to Cyclobenzaprine and Alcohol

It is possible to become addicted to cyclobenzaprine, but the likelihood rises dramatically when alcohol is used in conjunction with this medication. Considered a substance use disorder, addiction is a long-term brain disorder that is exacerbated by the abuse of both alcohol and cyclobenzaprine together, a condition known as polydrug use.

Medical detoxification, which involves 24-hour observation over several days to remove these substances and manage potential withdrawal symptoms, is typically the first step in treating alcohol and cyclobenzaprine abuse. Withdrawal symptoms can range in severity from mild manifestations like achiness and sweating to severe ones like tremors and vomiting.

Medication may be given during detox to lessen the symptoms of withdrawal, and fluids may be provided to stay hydrated. Throughout this taxing phase of your treatment, the addiction care teams and medical professionals on-site offer support.

It may be suggested to undergo inpatient treatment after detox. Psychological therapy, such as behavioral therapies and 12-step programs, is frequently required for polydrug abuse. Evidence-based treatments such as Dialectical Behavior Therapy (DBT), Motivational Interviewing (MI), Cognitive Behavioral Therapy (CBT), and group, family, and couples therapy are used to address the behavioral and psychological aspects of addiction, regardless of the primary substance abuse.

If you need treatment for other medical conditions, your home environment isn’t supportive, or you need an intensive, structured program, it’s best to consider inpatient treatment. Partial Hospitalization (PHP), Intensive Outpatient Treatment (IOP), Outpatient Treatment (OP), and Aftercare are among the additional addiction treatment programs offered.

Aftercare programs provide a network of support and help with housing, legal, and financial needs, offering ongoing support following the completion of drug use treatment. These initiatives promote recovery and enhance patients’ physical and mental health after treatment.

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Muscle Relaxers Cyclobenzaprine, Soma, Baclofen, their Side Effects, Warnings, Types & Risks

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Sources
  1. Winek CL Jr, Wahba WW, Winek CL. Drowning due to cyclobenzaprine and ethanol. Forensic Sci Int. 1999 Mar 15;100(1-2):105-8. doi: 10.1016/s0379-0738(98)00161-3. PMID: 10356778. Related Reading: Cyclobenzaprine And Alcohol, Cyclobenzaprine Alcohol, Cyclobenzaprine With Alcohol, Cyclobenzaprine Interactions With Alcohol, Alcohol And Cyclobenzaprine, Cyclobenzaprine Side Effects With Alcohol, Cyclobenzaprine Alcohol Interactions,
  2. Messiha FS, Barnes CD. Cyclobenzaprine and ethanol interaction. Pharmacol Biochem Behav. 1979 Jun;10(6):947-9. doi: 10.1016/0091-3057(79)90074-1. PMID: 482318. Related Reading: Cyclobenzaprine And Alcohol, Cyclobenzaprine Alcohol, Cyclobenzaprine With Alcohol, Cyclobenzaprine Interactions With Alcohol, Alcohol And Cyclobenzaprine, Cyclobenzaprine Side Effects With Alcohol, Cyclobenzaprine Alcohol Interactions,
  3. Khan I, Kahwaji CI. Cyclobenzaprine. [Updated 2023 Aug 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK513362/
  4. Medline Plus – Cyclobenzaprine – https://medlineplus.gov/druginfo/meds/a682514.html
  5. FDA Access Data – Flexeril (Cyclobenzaprine) – https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/017821s045lbl.pdf
  6. DEA – Cyclobenzaprine – https://www.deadiversion.usdoj.gov/drug_chem_info/cyclobenzaprine.pdf
  7. Label: Cyclobenzaprine — cyclobenzaprine hydrochloride tablet, film coated. (2019). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b12fb4ea-182e-462b-b6ed-cfd2f6bb71e8
  8. Elder NC. Abuse of skeletal muscle relaxants. Am Fam Physician. 1991 Oct;44(4):1223-6. PMID: 1927837.
  9. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Muscle Relaxants. [Updated 2017 Jan 30]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK548375/
  10. Witenko, C., et al. (2014). Considerations for the appropriate use of skeletal muscle relaxants to manage acute low back pain. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103716/
  11. Borenstein DG, Korn S. Efficacy of a low-dose regimen of cyclobenzaprine hydrochloride in acute skeletal muscle spasm: results of two placebo-controlled trials. Clin Ther. 2003 Apr;25(4):1056-73. doi: 10.1016/s0149-2918(03)80067-x. PMID: 12809957.
  12. Long-term Use of Cyclobenzaprine for Pain: A Review of the Clinical Effectiveness [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Feb 23. PMID: 25763449.