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How Long Do Amphetamines Stay In Your System?

How Long Does It Take To Feel Effects?

Amphetamines can make people feel more alert, and are prescribed for problems like depression and attention deficit order. Amphetamines can produce euphoria, and so are manufactured for recreational use. Ongoing use can lead to dependence, which can be as hard to recover from as dependence on heroin or cocaine. How long do amphetamines stay in your system? The effects of amphetamine take place fairly quickly, often in less than an hour, and are similar to cocaine but last longer.

When chronic heavy users abruptly discontinue amphetamine use, many report a time‐limited withdrawal syndrome that occurs within 24 hours of their last dose. Amphetamine withdrawal symptoms are sufficiently severe to cause relapse to drug use in the absence of contained environments. 

Amphetamine Drug Test

Amphetamines were also once used to treat narcolepsy and obesity, but this is less common today. Amphetamine is a Schedule II drug, meaning it has a high potential for drug addiction, with use potentially leading to severe psychological or physical dependence. How long do amphetamines stay in your system? It can be detectable for up to three months with certain tests. [1]

  • Urine: Up to five days
  • Blood: Up to 48 hours
  • Saliva: Up to five days
  • Hair: Up to three months
How Long Do Amphetamines Stay In Your System?
How long do amphetamines stay in your system? The peak effects of amphetamines occur 1 to 3 hours after a person takes them by mouth, and effects last for as long as 7 to 12 hours.

Amphetamine Drug Test Urine

If you take amphetamine often, it may show up in your urine for up to a week after using it. How long do amphetamines stay in your system? Results only show that amphetamine was in your system at the time of the test. A positive test result should be confirmed by a lab. Healthcare providers diagnose amphetamine use disorder only after a physical exam.

Blood Test For Amphetamines

This test measures the amount of a drug called amphetamine in your blood. This drug is a central nervous system stimulant. This group of drugs also includes methamphetamine, or “meth.” The test is most commonly used to screen for drug use. It’s often required by the court system and some workplaces.

Amphetamine Hair Drug Test

Amphetamine, like many other drugs, can be detected with a hair follicle drug test for up to 90 days. Hair drug tests have the longest detection period, and can typically detect drug use for up to 90 days. How long do amphetamines stay in your system? Depending on the drugs used, a hair sample can sometimes help determine when drug use occurred and whether it’s been discontinued.

Amphetamine Drug Saliva Tests

A mouth swab drug test is a screening test used to detect substance use. It’s also referred to as a saliva drug test or oral fluids drug test. Saliva tests are being used more often as an alternative to urine drug tests. They’re easier to administer.

They’re used for everything from pre-employment screening and random or period testing to post-accident testing. Some police forces also use saliva drug tests for roadside drug testing when they suspect someone’s driving under the influence of amphetamines or other substances.

Amphetamine Withdrawal

The experience of withdrawal from amphetamines is clinically severe and it is during this period that reports of suicidal ideation and attempts are noted. Amphetamine-dependent individuals trying to discontinue or to cut down the use of the drug by self‐help or even formal drug addiction treatment commonly relapse, as a single use of amphetamine immediately removes discomfort and institutes a sense of well‐being or euphoria. As the initial phase of treatment requires cessation of use, amphetamine withdrawal compromises long‐term success for some individuals with severe amphetamine dependence to achieve protracted abstinence.

How Long Do Amphetamines Stay In Your System?
How long do amphetamines stay in your system? How long they last inside the body depends on several factors, including age, weight, dosage, and more.

The severity of amphetamine withdrawal symptoms is greater in amphetamine-dependent individuals who are older and who have more extensive amphetamine use disorders. How long do amphetamines stay in your system? Withdrawal symptoms typically present within 24 hours of the last use of amphetamine, with a withdrawal syndrome involving two general phases that can last 3 weeks or more.

The first phase of this withdrawal syndrome is the initial “crash” that resolves within about a week. The most immediate symptoms occur during this “crash” period and are observed to resolve during the first week of abstinence.

Severe symptoms in the “crash” phase of amphetamine withdrawal include increases in sleep (averaging 2‐3 hours more per night than controls, but with poor sleep quality, light sleep, frequent awakening, and not feeling clearheaded on arising), increases in appetite, and decreases in complaints of depression.

A subacute, protracted set of withdrawal symptoms that generally resolve in 3 weeks and that are not as well defined, include continued sleep disturbances (mild hypersomnia or insomnia and continued increased appetite. Although the most severe symptoms occurring during amphetamine withdrawal resolve in a week or less, some symptoms may continue for weeks or months. [2]

Amphetamine Withdrawal Symptoms

In 2006, 24.7 million individuals aged 15‐64 consumed amphetamine-type stimulants. Among chronic users of amphetamines, evidence is accruing to describe the range of public health problems attributable to sustained heavy use of the drug. Medical consequences of chronic use of amphetamines include cardiovascular insults, cognitive dysfunction, and infectious disease.

Some of the common amphetamine withdrawal side effects and symptoms include: [3]

  • Fatigue and increased need for sleep
  • Increased appetite
  • Bodily movements and twitches
  • Slowed reaction and movement
  • Aches and pains
  • Irritability and/or agitation
  • Dreams that are often vivid and sometimes unpleasant
  • Depression

Withdrawal from amphetamines is usually not life-threatening. However, it can be extremely uncomfortable and trigger a relapse. Detoxing amphetamine under the supervision of medically trained professionals may reduce the likelihood of relapse.

How long do amphetamines stay in your system? Chronic amphetamine users may have experienced paranoia and hallucination. A minority of individuals who use amphetamines develop full‐blown psychosis requiring care at emergency departments or psychiatric hospitals. In such cases, symptoms of amphetamine psychosis commonly include paranoid and persecutory delusions as well as auditory and visual hallucinations in the presence of extreme agitation.

More common (about 18%) is for frequent amphetamine users to report psychotic symptoms that are sub‐clinical and that do not require high‐intensity intervention. Clinical reports suggest the development of amphetamine psychosis and of sub‐clinical psychosis symptoms is related to the individual’s lifetime history of amphetamine use, i.e., cumulative quantity and frequency of exposure to amphetamines. [4]

How long do amphetamines stay in your system? Symptoms of amphetamine withdrawal during the initial days of abstinence from chronic amphetamine use can prompt individuals to return to regular drug use. No medications demonstrate significant effects over placebo in reducing symptoms of acute amphetamine withdrawal. [5]

The mainstay of managing amphetamine withdrawal and addiction treatment is supportive care and counseling.

Amphetamine Withdrawal Treatment

Stimulant withdrawal, which occurs following cessation of chronic cocaine or amphetamine use, can
produce a wide range of dysphoric symptoms:

  • Following binge use, individuals may initially experience a “crash” period, which is characterized by symptoms of depression, anxiety, agitation and intense drug craving.
  • During the intermediate withdrawal phase, individuals may experience fatigue, a loss of physical and mental energy, and decreased interest in the surrounding environment.
  • How long do amphetamines stay in your system? During the late withdrawal phase, individuals may experience brief periods of intense drug craving, such that objects and people in the addicted person’s life can become a conditioned trigger for craving and relapse. [6]
How Long Do Amphetamines Stay In Your System?
Understanding how long do amphetamines stay in your body is helpful; however, knowledge alone will not prevent withdrawal symptoms and is often not enough to break the cycle of addiction to stimulants. 

Treatment of stimulant abuse requires a comprehensive assessment of the patient’s psychological, medical,
forensic, and drug use history. Moreover, because information obtained from chemically dependent persons
may be incomplete or unreliable, it is important that patients receive a thorough physical examination,
including blood and supervised urine samples for analysis. The clinician must be aware that polydrug
abuse is common. Patients may ingest large amounts of one or more drugs at potentially lethal doses;
therefore, the physician must be aware of the dangers of possible drug combinations, such as cocaine and
alcohol or heroin.

How long do amphetamines stay in your system? It can last up to three months. Pharmacological intervention may be necessary during stimulant-induced drug states. For example,
neuroleptics may be useful in controlling stimulant-induced psychosis or delirium, and anti-craving agents with a fast onset of action may be helpful during the early withdrawal period. During the late withdrawal phase, when depression may be present, antidepressants may be an appropriate choice for treatment.

Treatment medications can be given on an inpatient or outpatient basis. However, if medications are used
for outpatient treatment, the clinician must warn the patient of the potential adverse interactions between cocaine and the prescribed medication.

For instance, high blood pressure can result from the release of epinephrine by cocaine combined with the reuptake blockade by the tricyclic, although later in the course of treatment, tricyclics decrease the sensitivity of the postsynaptic adrenergic receptors.

Does Amphetamine Show Up on a Drug Test?

Yes, amphetamines stay in your system for between two and five days. How long do amphetamines stay in your system? Different amphetamines stay in the body for different lengths of time. In general, amphetamines stay in urine for up to four days and in hair for 90 days.

Health care providers may order amphetamine tests to determine whether their patients are taking the proper dose. Similarly, amphetamine tests may be required in professional settings while employees are undergoing substance abuse treatment.

Medical amphetamine detox helps smooth the withdrawal process, reduce side effects, prevent serious complications, and lessens amphetamine cravings. Overall, these medications offer a decent start towards recovery and help to maintain sobriety long-term. Opioid detox has to be followed with counseling, education and awareness, family and individual therapy, and support groups that can aid an individual in their attempt to stop using drugs and continue sobriety.

How long do amphetamines stay in your system? Worry no more. We Level Up TX addiction treatment center is here to help individuals successfully complete the drug detox process and to address psychological, physical, and spiritual issues connected to drug abuse. Qualified doctors, nurses, therapists, and addiction cases managers will be with you throughout the recovery process to ensure you have the support you need.

We also have the expertise to treat dual-diagnosis, which is common among amphetamine users. Since amphetamine abuse can lead to a co-occurring mental health disorder, such as anxiety, depression, suicidal thoughts, our treatment program is tailored to address these disorders at the same time.

Targeted individual counseling and group therapy sessions, along with other complementary therapies, educational lectures, and relapse prevention seminars are used to address the underlying factors for their insomnia and subsequent Lunesta addiction. Clients are taught to confront these issues and deal with Lunesta cravings by using healthy coping skills.

Reclaim your life, call us to speak with one of our treatment specialists. Our specialists know what you are going through and will answer any of your questions such as how long do amphetamines stay in your system

Your call is private and confidential and there is never any obligation.


[1] How Long Does Amphetamine Stay in Your System? –
[2] Treatment for amphetamine withdrawal – National Center for Biotechnology InformationU.S. National Library of Medicine
[3] How Long Do Amphetamines Stay In Your System? Amphetamine Withdrawal Symptoms and Timeline –
[4] Treatment for amphetamine psychosis – National Center for Biotechnology InformationU.S. National Library of Medicine
[5-6] Treatment of Acute Intoxication and Withdrawal from Drugs of Abuse – The Textbook of Substance Abuse Treatment, second edition. Editors: Marc Galanter, MD and Herbert D Kleber, MD